![]() It would be my pleasure to explore that with you. What informs your life? What defines you? If I can support you in thinking about that distinction, and how it pertains to your professional world, please let me know. Listening to that recent broadcast took me back to the time years ago when I vowed that cancer would not define me, although I can say it certainly informed my perspective on life and continues to do so (in a healthy way). INFORM, verb transitive Latin informo, to shape in and formo, forma, form. My work as a coach informs my professional life and imbues much of what I do. Websters Dictionary 1828 Online Edition is an excellent reference for. The desire to have wisdom, integrity and courage helps to shape my actions and beliefs (at least on my best days). I hope some of those attributes might someday define me. So, what does inform my life? Caring, curiosity, a desire to help others, an innate sense of joy, and a strong desire for peace is what I believe animates me. How might I be different if I let those inform my thoughts and behavior, but not define them? Perhaps there is something about choice that creates part of the distinction between what defines and what informs us. Things like circumstances, fears, insecurities, and certain long-held beliefs came to mind. But that got me wondering about what I all too often allow to define me. Some might say “lover of all things chocolate” defines me they have a point there, but I hope that a brownie compulsion isn’t an essential part of my nature. Now, my sons would say being a mother defines me (perhaps more than it should, considering my sons are grown men now). In thinking about what really defines me, I came up with human being and woman for starters. Definition (verb) impart knowledge of some fact, state or affairs, or event to. The dictionary defines inform as “to animate or inspire.” Define includes among its definitions “to explain or identify the nature or essential qualities of to determine or fix the boundaries of.” inform - Dictionary definition and meaning for word inform. His distinction between “define” and “inform” struck me. Not long ago, I heard a snippet of a narrative on NPR of a man, unable to walk or stand since birth, who declared that his disability does not define him, but rather informs his life. Additional information pertinent to the review is available over the web at. We survey some representative applications, such as finding homologues, designing drugs, and performing large-scale censuses. Finally, bioinformatics is a practical discipline. ![]() The emphasis is on approaches integrating a variety of computational methods and heterogeneous data sources. Bioinformatics employs a wide range of computational techniques including sequence and structural alignment, database design and data mining, macromolecular geometry, phylogenetic tree construction, prediction of protein structure and function, gene finding, and expression data clustering. Additional information includes the text of scientific papers and "relationship data" from metabolic pathways, taxonomy trees, and protein-protein interaction networks. Our definition is as follows: Bioinformatics is conceptualizing biology in terms of macromolecules (in the sense of physical-chemistry) and then applying "informatics" techniques (derived from disciplines such as applied maths, computer science, and statistics) to understand and organize the information associated with these molecules, on a large-scale.Īnalyses in bioinformatics predominantly focus on three types of large datasets available in molecular biology: macromolecular structures, genome sequences, and the results of functional genomics experiments (e.g. Here we propose a definition for this new field and review some of the research that is being pursued, particularly in relation to transcriptional regulatory systems. The recent flood of data from genome sequences and functional genomics has given rise to new field, bioinformatics, which combines elements of biology and computer science.
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